The Sabiá virus, causing acute hemorrhagic and neurological syndrome, has been circulating in Brazil for about 142 years and is now mutating, according to genomic analyses of recent cases.

The Sabiá virus, known for its ability to cause an acute hemorrhagic and neurological syndrome, has been circulating in Brazil for approximately 142 years. Since 1990, four fatal cases have been recorded in the state of São Paulo. Recent genomic analyses of two cases from 2019 and 2020 reveal that the virus has undergone significant genetic changes over time.

These mutations explain why existing diagnostic tests may not detect the virus effectively. As a result, identifying new strains or outbreaks can be challenging without updated testing methods. Researchers emphasize the importance of continued surveillance to better understand and manage this potentially dangerous pathogen in the future.