A new study finds that lower-volume bowel preparation with 1 L polyethylene glycol is effective and acceptable for inpatient colonoscopy, with good tolerability and high willingness to repeat.
A recent study has found that lower-volume bowel preparation with 1 L polyethylene glycol (PEG)-ascorbate is an effective and acceptable option for inpatient colonoscopy. The study, published in the Annals of Internal Medicine, randomly assigned 665 hospitalized adults to receive either split-dose 1 L PEG-ascorbate, 2 L PEG-ascorbate, or 4 L PEG. The results showed that adequate overall cleansing occurred in 82.0% of patients assigned to the 1 L group, 78.0% of those assigned to the 2 L group, and 78.5% of those assigned to the 4 L group.
The study also found that high-quality overall cleansing occurred in 46.9% of patients in the 1 L group, 35.3% of those in the 2 L group, and 37.4% of those in the 4 L group. For the right colon, high-quality cleansing occurred in 40.6% of patients in the 1 L group, 29.5% of those in the 2 L group, and 31.6% of those in the 4 L group. The researchers while tolerability was good across all regimens, the highest willingness to repeat was seen in the 1-L group, with 84.2% of patients willing to repeat the procedure.
The study's findings support the adoption of a low-volume regimen as a practical, patient-centered approach to inpatient bowel preparation. The authors note that the use of lower-volume bowel preparation can improve patient comfort and reduce the burden of bowel preparation on patients. The study was funded by Norgine, and the results have important implications for the management of colonoscopy in hospitalized patients.
The use of lower-volume bowel preparation has been a topic of interest in recent years, with several studies investigating its effectiveness and safety. The current study adds to the growing body of evidence supporting the use of lower-volume bowel preparation for inpatient colonoscopy. The results of the study are likely to be of interest to gastroenterologists, surgeons, and other healthcare professionals involved in the management of colonoscopy.
In conclusion, the study provides new insights into the effectiveness and safety of lower-volume bowel preparation for inpatient colonoscopy. The findings support the adoption of a low-volume regimen as a practical, patient-centered approach to inpatient bowel preparation, and are likely to inform clinical practice and guidelines for the management of colonoscopy in hospitalized patients. As the field of gastroenterology continues to evolve, it is likely that we will see further research into the use of lower-volume bowel preparation and its potential benefits for patients undergoing colonoscopy.
