Gavi, the global vaccine alliance committed to protecting children in the world’s poorest regions, has voiced deep disappointment following the United States’ abrupt withdrawal of funding over unsubstantiated vaccine safety concerns.

During a high-level summit in Brussels, organized to secure financial pledges for Gavi’s next five-year plan, a surprise video from US Health Secretary Robert F. Kennedy Jr cast a shadow over proceedings. In the video, Kennedy accused Gavi of promoting unsafe vaccines and failing to prioritize patient health — statements Gavi officials firmly rejected.

Gavi CEO Dr. Sania Nishtar stated, “We were disappointed to see the video and strongly disagree with many of the points raised. Despite this unfortunate development, we remain hopeful about maintaining a constructive relationship with the United States.”

The US decision is particularly critical as it contributes approximately 13% of Gavi’s core budget. Kennedy’s video claimed that Gavi must “re-earn public trust” before the US would consider further support, calling into question the group’s handling of vaccine safety — particularly regarding the DTPw vaccine (diphtheria, tetanus, pertussis), commonly administered in low-income countries.

In response, Gavi defended the use of DTPw, stating it provides stronger and longer-lasting protection against life-threatening diseases in regions with limited access to healthcare. “The benefits of the vaccine far outweigh the temporary side effects in high-risk settings,” Gavi clarified.

Despite the US withdrawal, Gavi managed to raise over $9 billion at the summit — a strong figure though slightly below its $11.9 billion goal. The funds aim to support immunization efforts for 500 million children against preventable diseases worldwide by 2030.

Dr. Nishtar remained optimistic, emphasizing the overwhelming demand for vaccines across supported nations. “In the field, we see long queues of mothers seeking vaccinations for their children. There is immense trust in Gavi’s mission.”

European countries and the European Union collectively pledged over €2 billion, while the Bill & Melinda Gates Foundation contributed $1.6 billion — demonstrating sustained global support for child vaccination efforts despite geopolitical setbacks.

As vaccine-preventable disease outbreaks such as measles and yellow fever rise globally, Gavi’s role remains vital in bridging health equity gaps and countering misinformation that threatens global immunization progress.